Concurrent analysis of whole-genome DNA methylation and single-cell RNA sequencing data from COVID-19 patients and controls reveals gene regulatory alterations in airway epithelial and immune cells.

A new study highlights the placenta’s role in neuropsychiatric development, showing that DNA methylation influences gene ...

This research leverages the power of whole-genome bisulfite sequencing to characterize DNA methylation patterns ... silenced while the paternal allele is active, or vice versa.

The team's findings suggest Spirodela focuses on silencing potentially active transposons—a clear ... marks on degenerate ...

However, there are certain hurdles to overcome. One significant challenge is the technical challenges in methylation analysis. The biggest problem for DNA methylation is diversity among cells produced ...

The researchers examined 850,000 sites of DNA methylation, where small chemical tags called methyl groups are added to DNA. This process can alter gene expression without changing the underlying ...

DNA methylation is a key epigenetic mechanism ... similar to those observed with intrauterine exposure to tobacco or active smoking. This underlines the urgency of implementing comprehensive ...