the authors show that targeting both glutamine degradation and mTOR inhibition effectively kills PI3K-altered cancer cells in pre-clinical and clinical settings for T-cell acute lymphoblastic ...

Children between 2-9 years old who lived within 3.1 miles of wells with high activity faced the greatest risk of developing acute lymphocytic leukemia, compared to those living farther away from ...

B-cell acute lymphoblastic leukemia (B-ALL) is a life-threatening and highly aggressive form of blood cancer. It is the most common childhood cancer, making up 35% of pediatric cancer cases ...

We combine genetic mouse models and pre-clinical mouse models using patient samples to study genes involved in pediatric (acute lymphoblastic ... leukemia and acute myeloid leukemia) leukemias. Dr.