Because newly weaned Cftr –/– mice are weak, solid chow was soaked with laxative during the first week after weaning. Subsequently, part of these animals were followed-up for a longer period ...

The three key functions of the Core are listed below: These CF mouse models produce no functional Cftr mRNA or protein, and are particularly useful to stufy consequences of the electrophysiological ...

When knockout mice were housed in a sterile environment ... About 20 years ago, it was determined that CF is caused by mutation of the gene CFTR. Despite that discovery, however, the underlying ...