A CRISPR/Cas9-based galactose screening identifies key mitochondrial genes involved in OXPHOS and oxidative metabolism, ...

Researchers have developed a machine learning model that predicts Cas9 proteins that can be tailored with designer properties for therapeutic use.

Genome editing has advanced at a rapid pace with promising results for treating genetic conditions—but there is always room ...

Latest study leverages new constructs for nuclear localization signal (NLS) sequences to improve editing efficiency in human ...

Using gene editing with CRISPR-Cas9, the team has been able to study these proteins without altering ... Dec. 13, 2024 — Microorganisms produce a wide variety of natural products that can be ...

Genome editing has advanced at a rapid pace with promising results for treating genetic conditions-but there is always room for improvement.

Collaborating with CRISPR-Cas9 co-inventor Jennifer Doudna and Jill Banfield at UC Berkeley, Steven Jacobsen, a distinguished professor of molecular, cell and developmental biology at UCLA ...

CRISPR/Cas9 remains the most powerful tool to generate ... To put it in numbers: with their previous vector, a CRISPR screen looking for all double knockouts of just 20 genes was estimated to ...

Cas9, the first Cas protein repurposed for cutting DNA, introduces double-strand breaks that recruit DNA repair machinery. Despite its successes, the CRISPR-Cas9 system has several limitations, ...

In a new development, researchers have successfully created an efficient two-line system for hybrid seed production in Brassica napus (rapeseed) using CRISPR/Cas9 gene editing combined with the RUBY ...