Advances in the gene-editing technology known as CRISPR-Cas9 over the past 15 years have yielded important new insights into the roles that specific genes play in many diseases. But to date this ...

and a central dogma of biology is that this information flows from DNA to RNA to proteins. But only two percent of the human genome actually encodes ... Nov. 6, 2024 — The CRISPR tool is capable ...

Because RNA lies at the heart of gene expression, extracting it from cells is a common procedure in many cell biology, molecular biology, and biochemistry laboratories. "Obtaining high-quality, intact ...

Bioengineering professor and The Grainger College of Engineering's Dean, Rashid Bashir, led a team of researchers in a ...

Advances in the gene-editing technology known as CRISPR-Cas9 over the past 15 years have yielded important new insights into the roles that specific genes play in many diseases.

a type III CRISPR for RNA editing, and a Cas13 loaded with multiple guide RNAs for multiplexed targeting. Learn more about CRISPR in this summary article. Avoiding CRISPR Off-Target Effects by ...

This protein can easily be programmed to find and bind to almost any desired target sequence, simply by giving it a piece of RNA to guide it in its search. When the CRISPR Cas9 protein is added to ...

Enter the anti-CRISPR protein AcrVIB1, a promising inhibitor whose exact function has remained a mystery—until now. A research team from the Helmholtz Institute for RNA-based Infection Research ...

Together, we intend to accelerate the field of next-generation medicines in mRNA and CRISPR, using best-in-class chemistries, processes, and proprietary technologies like CleanCap ® analogs ...