Advances in the gene-editing technology known as CRISPR-Cas9 over the past 15 years have yielded important new insights into ...

Because RNA lies at the heart of gene expression, extracting it from cells is a common procedure in many cell biology, molecular biology, and biochemistry laboratories. "Obtaining high-quality, intact ...

Bioengineering professor and The Grainger College of Engineering's Dean, Rashid Bashir, led a team of researchers in a ...

a type III CRISPR for RNA editing, and a Cas13 loaded with multiple guide RNAs for multiplexed targeting. Learn more about CRISPR in this summary article. Avoiding CRISPR Off-Target Effects by ...

and a central dogma of biology is that this information flows from DNA to RNA to proteins. But only two percent of the human genome actually encodes ... Nov. 6, 2024 — The CRISPR tool is capable ...

This protein can easily be programmed to find and bind to almost any desired target sequence, simply by giving it a piece of RNA to guide it in its search. When the CRISPR Cas9 protein is added to ...

At the heart of this technology is the Cas9 protein, often likened to molecular scissors, capable of cutting strands of DNA at specific locations dictated by a single guide RNA. With this ...

Enter the anti-CRISPR protein AcrVIB1, a promising inhibitor whose exact function has remained a mystery—until now. A research team from the Helmholtz Institute for RNA-based Infection Research ...

Together, we intend to accelerate the field of next-generation medicines in mRNA and CRISPR, using best-in-class chemistries, processes, and proprietary technologies like CleanCap ® analogs ...

Advances in the gene-editing technology known as CRISPR-Cas9 over the past 15 years have yielded important new insights into the roles that specific genes play in many diseases. But to date this ...