ETX-19477 is a potent, selective inhibitor of poly (ADP-ribose) glycohydrolase (PARG), an enzyme that plays a role in the DNA ...
The discovery could pave the way for new treatments, improved risk prediction, and earlier intervention for brain metastases.
8hon MSN
How major nuclear protein complexes control specialized gene regulation in cancer and beyond
Precision and timing of gene expression is essential for normal biological functions and, when disrupted, can lead to many ...
Scientists at St. Jude Children's Research Hospital have revealed previously unappreciated roles for the retrotransposon LINE ...
News-Medical.Net on MSN
Low-dose megestrol strengthens hormone therapy in ER-positive breast cancer
Low-dose megestrol enhances hormone therapy for ER-positive breast cancer, reducing tumor proliferation and improving ...
A large-scale international study, led by researchers from the Gray Faculty of Medical and Health Sciences at Tel Aviv ...
Megestrol, which helps treat hot flashes associated with menopause, may have the added benefit of slowing the growth of ...
A class of ultrasmall fluorescent core-shell silica nanoparticles developed at Cornell is showing an unexpected ability to ...
News-Medical.Net on MSN
Jumping genes reshape cancer genomes through 3D chromatin interactions
Scientists at St. Jude Children's Research Hospital have revealed previously unappreciated roles for the retrotransposon LINE-1 in shaping the cancer genome structure and regulation.
A cancer vaccine that maximizes immunity by injecting inactivated cancer cells into the body is beginning a Phase 1 clinical ...
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