Visualization in the UMAP space of samples corresponding to the subtypes ER+ (a), HER2+ (b), and TN (c). The samples were categorized by cancer subtype and integrated. Cells are color-coded according ...

Triple-negative breast cancer (TNBC) accounts for 15% to 20% of breast cancers. It is a heterogeneous disease, not only on the molecular level, but also on the pathologic and clinical levels. TNBC is ...

Patient-derived xenograft (PDX) models are emerging as a transformative tool in colorectal cancer (CRC) research, offering unparalleled insights into tumor biology, drug resistance, and personalized ...

A method has been reported by researchers from Tsinghua University in China, which enables the efficient and high-throughput production of lung cancer assembloids. These assembloids are ...

Efficacy and safety of durvalumab plus tremelimumab versus standard chemotherapy for non-small cell lung cancer: A systematic review and meta-analysis of phase III randomized controlled trials.

The Li-Fraumeni syndrome (LFS) and its variant form (LFL) is a familial predisposition to multiple forms of childhood, adolescent, and adult cancers associated with germ-line mutation in the TP53 ...

The GA4GH is uniting researchers worldwide to share genomic data responsibly, set open standards, and improve oncology care ...

The gut microbiome serves as both a biomarker and therapeutic target in diseases like obesity, metabolic syndrome, and ...

In recognition of Breast Cancer Awareness Month, join us for a live webinar to uncover the complexity of tumor biology and the surprising resilience of normal tissue. This event will feature two ...

A new generation of personalized cancer vaccines is taking shape through the use of neoantigen-based dendritic cell (DC) ...