Now, Johns Hopkins Medicine scientists say they have shed new light on how bacteria protect themselves from certain phage ...

Unlike classic phage therapy, which uses one or more types of phages to infect and lyse specific bacterial strains, the crux of this new approach is using these specialized viruses to supply ...

of invading genetic parasites like bacteriophages (phages); viruses that infect—and eventually kill—bacterial cells. They consist of two main components; the CRISPR array, which stores immune ...

Bioengineering professor and The Grainger College of Engineering's Dean, Rashid Bashir, led a team of researchers in a ...

The researchers found one subfamily of telomere-targeting transposons that coopted a CRISPR system -- normally used by bacteria to defend against viruses -- to target and insert itself into the ...

Scientists use CRISPR systems to genetically manipulate specific bacterial species, for instance those found in the mouse gut microbiome, to find new ways to promote health and treat disease. (1) ...

But if we use nature as a guide, we can look throughout different microbes and see how large these CRISPR arrays can get, and I think this defines a theoretical bound, and there's one bacterial ...

The researchers found one subfamily of telomere-targeting transposons that coopted a CRISPR system – normally used by bacteria to defend against viruses – to target and insert itself into the ...

Antibiotic resistance is a global concern that threatens our ability to prevent and treat bacterial infections ... for Genomic Biology have developed a CRISPR-enriched metagenomics method for ...

This is exemplified by granted US patent US11,517,582, which covers the use of CRISPR-Cas systems to achieve selective killing of bacteria by at least 1000-fold in situations where bacteria are ...