DNA methylation is one of several epigenetic ... and a range of birth defects that appear to be caused by defective imprinting mechanisms (Robertson, 2005). The results of these studies will ...

Despite what we know about gene imprinting, X chromosome inactivation, DNA methylation, and the various transcription factors involved, much needs to be discovered before we can fully explain any ...

Some of these methylation changes are caused by genetic differences in genomic sequence of DNA, while others are due to parental imprinting—a mechanisms for expression of specific genes only ...

Epigenetics refers to information in the human genome other than that in the DNA sequence. The field of epigenetics ... of research on the effects of the early environment on imprinting methylation in ...

This is published in Nature Communications in the paper, “Atlas of imprinted and allele-specific DNA methylation in the human body.” “Genomic imprinting is set early during development ...

A well-studied DNA methylation-based phenomenon is genomic imprinting (ie, genotype-independent parent-of-origin effects). Objective We aimed to elucidate: (1) the effect of exercise on DNA ...

DNA methylation is a fundamental epigenetic mechanism in which a methyl group is added onto a nucleotide, commonly cytosine. DNA methylation affects many biological processes, including gene ...

However, there are certain hurdles to overcome. One significant challenge is the technical challenges in methylation analysis. The biggest problem for DNA methylation is diversity among cells produced ...

"Genomic imprinting is set early during development ... More information: Atlas of imprinted and allele-specific DNA methylation in the human body, Nature Communications (2025).

More information: Atlas of imprinted and allele-specific DNA methylation in the human body, Nature Communications (2025). DOI: 10.1038/s41467-025-57433-1 Provided by Hebrew University of Jerusalem ...