Adrenomedullin (ADM) inhibits endothelial insulin signaling, contributing to obesity-associated insulin resistance, according ...

A knockout mouse is a laboratory mouse in which one or more genes have been turned off or "knocked out." To create a knockout mouse, scientists genetically engineer the animal by disrupting a gene ...

It’s a new way to create “bi-paternal” mice that can survive to adulthood—but human applications are still a long way off.

A research group led by Wei Li at the Chinese Academy of Sciences has created mice born from two male parents and capable of ...

Researchers find that certain antioxidant enzymes, called selenoproteins, significantly contribute to fighting cell aging. The team used a gene knockout mouse model to help them study the effects of ...

Many foods are often advertised for their antioxidant properties. Antioxidants counteract what are known as reactive oxygen ...

They followed by isolating EVs from normal mice and knockout mice lacking the gene that encodes the BK potassium channel, and found the cargo in EVs from the knockout mice were very different in ...

They followed by isolating EVs from normal mice and knockout mice lacking the gene that encodes the BK potassium channel, and found the cargo in EVs from the knockout mice were very different in ...

Researchers develop a novel Tle6 gene hetero knockout mice model to understand the role of this gene in male fertility and find that its deficiency results in abnormal sperm structure, reduced ...

Megakaryocytes form a three-dimensional (3D) cage composed of laminin and collagen IV connected to the basement membrane surrounding them. This microarchitecture stabilizes megakaryocytes within their ...