A knockout mouse is a laboratory mouse in which one or more genes have been turned off or "knocked out." To create a knockout mouse, scientists genetically engineer the animal by disrupting a gene ...

The National Institutes of Health today awarded a set of cooperative agreements, totaling up to $52 million over five years, to launch the Knockout Mouse Project. The goal of this program is to ...

The University of California, Davis, has been awarded just over $12 million from the National Institutes of Health under the third and final five-year phase of the Knockout Mouse Phenotyping Project, ...

Making a knockout mouse: Step by step How are genes deleted or disrupted in a knockout mouse? In the past, making a knockout mouse was a major undertaking.

A drug commonly used to treat type 2 diabetes may reduce excess fluid in the brains of patients with hydrocephalus, which could help treat the disease less invasively than current treatments, ...

Researchers at Baylor College of Medicine have received a grant for more than $12 million from the National Institutes of Health for a third five-year phase of the Knockout Mouse Phenotyping Program ...

More than 70 genes have been linked to autism spectrum disorder (ASD), a developmental condition in which differences in the brain lead to a host of altered behaviors, including issues with ...

Born as a pandemic diversion in 2020, “Knockout” is finally a fully baked dance performance, premiering with a two-week run kicking off the spring edition of Steppenwolf’s LookOut Series ...

To generate a tissue specific knockout mouse, researchers breed a mouse bearing a Cre transgene under a tissue- or cell-type specific or inducible promoter (A) with a homozygous floxed mouse (B). The ...

New research shows that retinal neurons can rewire to preserve vision in retinitis pigmentosa, a genetic disease causing blindness.

'Knockout City' is going offline forever this summer, indie developer Velan Studios has announced in a new blog post.

Scientists at the Jules Stein Eye Institute at the David Geffen School of Medicine at UCLA have discovered that certain ...