Human Lie Detector Charlie Cale is back, with guest stars including Kumail Nanjiani, Cynthia Erivo, Katie Holmes and John Mulaney.

The premise established in Season 1 has Charlie fleeing from the mob, which is another reason for her transient life on the road. But “Poker Face” doesn’t actually need a Big Bad to justify her meandering existence,

In the weekly comedic mysteries of “Poker Face” Natasha Lyonne is Charlie, who has the ability to tell when people are lying.