Since the time of those experiments, it has become apparent that the efficacy of thymic negative selection in purging the T cell repertoire of potentially self-reactive cells is enhanced by the ...

A discovery published in Nature Immunology has shed light on why the immune system is less aggressive toward self-antigens, ...

Researchers from the La Jolla Institute for Immunology recently used the Expanse supercomputer at the San Diego Supercomputer ...

How are humans contributing to negative selection? It's a part of evolution that can also drive some species to extinction; models of negative selection help us understand biodiversity.