San Francisco, CA - Researchers at UCSF have for the first time identified the gene encoding an ADP platelet receptor that is the target of antithrombotic agents. Their report appears in the January ...

Platelets play a crucial role in hemostasis; activating and aggregating to arrest bleeding following vascular injury. Platelet activation is a complex and dynamic process, involving the co-ordination ...

This is a preview. Log in through your library . Abstract Glycoprotein (GP) V is a major substrate cleaved by the protease thrombin during thrombin-induced platelet activation. Previous analysis of ...

Blood platelets have a receptor for macromolecular adhesive glycoproteins, located on a heteroduplex membrane glycoprotein complex (GPIIb/IIIa) that only becomes "exposed" when platelets are activated ...

Researchers led by Professor Steve Watson and Dr Eleyna Martin from the Institute of Cardiovascular Sciences at the University of Birmingham have delivered a breakthrough for thrombosis researchers, ...

Platelets have multiple direct and indirect functions that integrate innate and adaptive antimicrobial host defences. Platelets actively sense signals of tissue injury and microbial infection via an ...

Please provide your email address to receive an email when new articles are posted on . SAN FRANCISCO — Although data suggest there is no benefit to pretreating most patients with platelet receptor ...

Following allogeneic hematopoietic stem cell transplantation (HSCT) patients may have an increased bleeding tendency in spite of a normal platelet count. Moreover, an association between chronic graft ...

The developing thrombus in a living mouse after vessel-wall injury (Panel A) is characterized by the deposition of platelets (red), tissue factor (green), and fibrin (blue). Platelet thrombus ...

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) bears an abundance of the characteristic spike protein, which mediates its entry into and fusion with the host cell, as well as ...

Phase I Clinical and Pharmacokinetic Study of the Novel Raf Kinase and Vascular Endothelial Growth Factor Receptor Inhibitor BAY 43-9006 in Patients With Advanced Refractory Solid Tumors CDP860 is an ...

Phase I Clinical and Pharmacokinetic Study of the Novel Raf Kinase and Vascular Endothelial Growth Factor Receptor Inhibitor BAY 43-9006 in Patients With Advanced Refractory Solid Tumors CDP860 is an ...