San Francisco 49ers Report

San Francisco 49ers, Browns

49ers 2nd Week 13 practice report has head-scratching injury update

The San Francisco 49ers in Week 13 made a significant change to how they're managing the health of one of their superstars.

49ers Webzone · 1d

49ers vs. Browns injury report: 5 players miss Wednesday’s practice

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Browns vs. 49ers Injury Report – Week 13, 2025

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Cooper Kupp injury update and status vs. the Vikings in Week 13 | Nov. 30, 2025

In Week 13, the Seattle Seahawks and Cooper Kupp meet the Minnesota Vikings at Lumen Field in Seattle, Washington.

Raiders Wire · 2h

Michael Mayer injury update and status vs. the Chargers in Week 13 | Nov. 30, 2025

Niners Wire · 5h

Brock Purdy injury update and status vs. the Browns in Week 13 | Nov. 30, 2025

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Tony Pollard injury update and status vs. the Jaguars in Week 13 | Nov. 30, 2025

Pollard has rushed for a team-leading 522 yards on 140 attempts (47.5 ypg), and has scored two rushing TDs.

Saints Wire · 5h

Devin Neal injury update and status vs. the Dolphins in Week 13 | Nov. 30, 2025

Niners Wire · 5h

Ricky Pearsall injury update and status vs. the Browns in Week 13 | Nov. 30, 2025

Dawgs By Nature on MSN

Browns, 49ers report: Christian McCaffrey, Browns RB sit out Thanksgiving practice

The Cleveland Browns and San Francisco 49ers both had a running back sitting out practice. Christian McCaffrey for 2nd day

22h

Browns, 49ers report: Christian McCaffrey, Trent Williams, Denzel Ward do not practice Wednesday

The Cleveland Browns and San Francisco 49ers kicked off their practice week on Wednesday with Thanksgiving just a sleep away. The Browns have been struggling but are hoping QB Shedeur Sanders can help lift the offense and DE Myles Garrett can continue to dominate the competition, setting impressive numbers to start the 2025 NFL season.

10h

Report: Brandon Aiyuk missed rehab appointments with 49ers

The San Francisco 49ers have voided a significant portion of the guaranteed money on star wide receiver Brandon Aiyuk's contract, and some new information

USA TODAY Touchdown Wire on MSN

49ers vs. Panthers injury report: San Francisco rules two out for MNF

The San Francisco 49ers will take on the Carolina Panthers on Monday, but they'll be without two players and could have two more miss the game.

12d

49ers Add Defensive Starter to Injury Report as Several Key Players Return

Ahead of their game against the Cardinals, the 49ers got a bunch of great health news, though they did add one player to the injury report.

1don MSN

49ers rumors: What ESPN insider is hearing about a Brandon Aiyuk trade after contract bombshell

After Brandon Aiyuk's guarantees for next season have been voided, Jeremy Fowler reports that the saga is "far from over" for the 49ers.

San Francisco 49ers vs. Cleveland Browns odds, tips and betting trends | Week 13 - November 30, 2025

Preview the NFL week 13 matchup between the San Francisco 49ers and Browns, including betting odds, tips, trends, and game information.