A new AI tool that models how variations in peptides change T cell receptor binding could help design immunotherapies with ...

New designer proteins created using an AI tool can selectively target peptide segments that bind to markers on diseased ...

Expression of exhaustion markers alone does not necessarily mean the cells are functionally exhausted, as these markers can be associated with T-cell activation.

Next, pre-washed and resuspended GMP ActiveMax ® Human T cell Activation/Expansion CD3/CD28 Beads (ACROBiosystems, Cat. No. GMP-MBS001) were added to the well at a 1:1 ratio.

Fluorescence imaging tracked nanoparticle localization and persistence post-injection, while immunohistochemical analyses assessed T cell activation markers, including CD8 and PD-1, within the tumors.

Cells were treated with varying concentrations of DHA, and CD4 + and CD8 + T cell activation markers (CD38 and HLA-DR) were measured via flow cytometry.

The immune cell repertoire is composed of many different cell types that are orchestrated in response to infection and other ...

In organoid monolayer T-cell co-cultures, the authors write, “gluten increased the proliferation of CD4+ T cells, expression of T-cell activation markers, and the release of interleukin-2, IFN ...

David Baker’s Nobel Prize-winning lab has generated AI-designed proteins to enhance the immune system's ability to detect and ...

Inflammation from viral infections promotes cancer metastasis, offering answers to why some cancers reawaken in humans.