New designer proteins created using an AI tool can selectively target peptide segments that bind to markers on diseased ...

Discover how lymphoid structures and germinal centers provide powerful prognostic insights into colorectal cancer.

A new AI tool that models how variations in peptides change T cell receptor binding could help design immunotherapies with ...

David Baker’s Nobel Prize-winning lab has generated AI-designed proteins to enhance the immune system's ability to detect and ...

Investigators led by Navdeep Chandel, Ph.D., the David W. Cugell, MD, Professor of Medicine in the Division of Pulmonary and ...

Expression of exhaustion markers alone does not necessarily mean the cells are functionally exhausted, as these markers can be associated with T-cell activation.

Marker Therapeutics, Inc. has announced a collaboration with Cellipont Bioservices to support the cGMP manufacturing of MT-601, its lead Multi-Antigen Recognizing (MAR)-T cell therapy, currently ...

Cells were treated with varying concentrations of DHA, and CD4 + and CD8 + T cell activation markers (CD38 and HLA-DR) were measured via flow cytometry.

For decades, dogma dictated that the immune system consisted of two separate branches. Cells of the innate system respond rapidly to molecular patterns shared by a broad array of pathogens. Meanwhile, ...