Lipid nanoparticles (LNPs) have enormous potential for the delivery of genomic medicine. One obstacle, however, is the lack of effective ways to target specific cell types. In order to target lung ...

Messenger ribonucleic acid (mRNA)-based therapeutics and the potential of mRNA as a treatment for various conditions has been researched for decades. A key challenge remains finding a delivery system ...

Yang Zhang, PhD, and Jinjun Shi, PhD, both of the Center for Nanomedicine and Department of Anesthesiology, Perioperative and Pain Medicine at Brigham and Women’s Hospital, are co-senior authors of a ...

A team of researchers based at the University of Toronto's (U of T) Leslie Dan Faculty of Pharmacy has discovered a novel ionizable lipid nanoparticle that enables muscle-focused mRNA delivery while ...

As I have written about previously, the IP and competitive landscape for mRNA and lipid nanoparticles is complex. Pioneers, mid-stage, and new market entrants must take careful consideration of this ...

The study was published in Nature Biotechnology last month and marks a shift in scientists’ understanding of how to ...

Generation LNP Advancements enhance potency and safety, expand delivery beyond the liver, and enable broader therapeutic ...

Researchers at the Icahn School of Medicine at Mount Sinai and collaborators have reported early success with a novel ...

A district court judge filed an order Tuesday denying a motion to dismiss a Northwestern lawsuit alleging Moderna infringed ...