Genetically modified mice lacking PPDPF were developed using CRISPR-Cas9, and additional models were created through ... leading to reduced NAD⁺ levels. Mice lacking PPDPF (knockout) developed more ...

In mice, both fasting and a high-fat diet (HFD ... followed by western blot analysis. The CRISPR/Cas9 system was utilized to generate Tet2 knockout cells. Lentiviruses were produced by co-transfecting ...

Researchers at Tel Aviv University have announced that they have successfully removed half of a tumor in a mouse's head using ... Aviv University was to use CRISPR-Cas9 to remove the protein ...

The global humanized liver mice model market is on a strong growth trajectory, fueled by the increasing prevalence of liver diseases and significant technological advancements in genetic engineering.

Mar. 26, 2025 — Many obese people report losing pleasure in eating rich foods -- something also seen in obese mice. Scientists have now discovered the reason. Long-term high-fat diets lower ...

In human cells, lipid droplets (LDs) predominantly contain either cholesteryl esters or triacylglycerols. This article ...

A research team from Helmholtz Munich and the Technical University of Munich has developed an advanced delivery system that ...

Knockout of INTS12 improved latency reactivation at the transcriptional level and is more specific to the HIV-1 provirus than AZD5582 & I-BET151 treatment alone. We found that INTS12 is present on ...

Various models have been generated using the CRISPR/Cas9 technology, which displaying a more accurate disease phenotype in various cell lines, such as stem cells, iPSCs, and transgenic animals ...