CRISPR libraries enable scientists to systematically investigate gene functions, identify novel drug targets, and develop personalized therapies.

One of the key challenges of the modern genomics era is studying the thousands of genes in a single human cell at scale. To ...

Genomics encompasses the study of a complete set of genes, their work process, and their way of interacting with each other and the environment. While it incorporates elements of genetics, the primary ...

A high throughput screen of >30,000 diverse repressor domains ... X-Repressors (ELXRs), making them more potent than current Cas9-based repressors. ELXR offers a promising epigenetic editing ...

This A-List features two lists of sequencing instrument providers: eight for NGS instruments and three for Sanger ...

A pair of privately-held developers of editing-based therapies have some successes to show for their recent efforts to ...

CRISPR-Cas9 technology has become a cornerstone of ... but BATF3 emerged as a standout candidate. In the CRISPRi screen, gRNAs that inhibited BATF3 were enriched in the CCR7-high population ...

Advances in the gene-editing technology known as CRISPR-Cas9 over the past 15 years have yielded important new insights into ...

Human extracellular matrices can be edited in their composition using the CRISPR/Cas9 system, leading to materials exhibiting tailored regenerative capacities.