News
11d
News Medical on MSNNew Assay Evaluates Chemical-Induced Epigenetic ShiftsChemicals used as food preservatives, flavoring agents, dyes, pesticides, cosmetics, cleaners, and other industrial materials ...
2d
News Medical on MSNExploring citrullination as a key regulator of gene expression and diseaseCitrullination, a transformative protein post-translational modification, is gaining recognition for its wide-ranging impact on cellular function and human disease.
Scientists at St. Jude Children’s Research Hospital used a series of cryo-EM structures to visualize dynamics pivotal to chromatin remodeling, a process implicated in cancer and developmental ...
Another company looking to initiate clinical trials with an epigenetic-editor-based treatment for hepatitis is nChroma Bio.
DNA demethylation of cytosines within CpG dinucleotides ... Tet1/3 thus act as determinants of CD8 T cell fates by promoting chromatin accessibility at TCR-responsive genes during T cell development.
To address these questions, we have characterized the accessibility ... chromatin capture. In chip loading, the nuclei yield was set at 5000 nuclei per sample. Chromium Single Cell Next GEM ATAC ...
Cas9, guided by a single-guide RNA (sgRNA)—a fusion of crRNA and tracRNA—recognizes a specific DNA target via the protospacer ... Petrub-seq for transcriptomic profiling and Petrub-ATAC for chromatin ...
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