4don MSN
DNA transcription is a tightly choreographed event: How RNA polymerase II regulates the dance
Life's instructions are written in DNA, but it is the enzyme RNA polymerase II (Pol II) that reads the script, transcribing ...
News-Medical.Net on MSN
Researchers uncover how a key transcription factor reads DNA in human cells
With a new study in the journal Cell, researchers at Stanford University and Stockholm University have contributed to ...
Ubiquitin pathway blockade reveals endogenous ADP-ribosylation marking PARP7 and AHR for degradation
Degradation mechanisms of transcriptionally active aryl hydrocarbon receptor (AHR) are unclear. This work reveals that PARP7 ...
Researchers at The University of Texas MD Anderson Cancer Center have shown that DNA inflexibility, or rigidity, inside the ...
The role of biomechanical cues in the progression of PM2.5-induced corneal disease was investigated, and PAI-2 was identified ...
AZoLifeSciences on MSN
Scientists Map How Transcription Factors Interpret DNA Sequences
With a new study in the journal Cell, researchers at Stanford University and Stockholm University have contributed to ...
News-Medical.Net on MSN
Breakthrough platform reveals the choreography of mammalian transcription
Life's instructions are written in DNA, but it is the enzyme RNA polymerase II (Pol II) that reads the script, transcribing ...
Background Eosinophilic oesophagitis (EoE) is a chronic allergic disease characterised by oesophageal epithelial remodelling, barrier dysfunction and inflammation. The transcription factor forkhead ...
DNA (deoxyribonucleic acid) is the nucleic acid polymer that forms the genetic code for a cell or virus. Most DNA molecules consist of two polymers (double-stranded) of four nucleotides that each ...
Background Chronic stress is a known risk factor for cancer metastasis. However, the underlying mechanisms, particularly ...
Background Hereditary haemorrhagic telangiectasia (HHT) and juvenile polyposis syndrome (JPS) can be caused by SMAD4 pathogenic variants. SMAD4 is a common transcription factor of the BMP/TGFβ ...
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