Emerging MRD tests show promise in enhancing breast cancer treatment by improving risk stratification and clinical outcomes ...

This manuscript makes a valuable contribution to the concept of fragility of meta-analyses via the so-called 'ellipse of insignificance for meta-analyses' (EOIMETA). The strength of evidence is solid, ...

The efficacy of immunotherapy varies significantly across different tumor types, and antigen heterogeneity has emerged as a key factor determining treatment outcomes. Tumors with high immunogenicity ...

Chimeric Antigen Receptor (CAR) T cell therapies have revolutionized cancer treatment—but so far, their success has been largely limited to blood cancers. Solid tumors, which account for around 90% of ...

Cancer doesn’t follow a linear path—it evolves, adapts, and forks. Even within a single tumor, individual cells behave differently. They mutate, diverge, and form heterogeneous clones that fuel ...

This is a useful tool for code-less analysis of patterns in cell migratory behaviours in vivo using intravital microscopy data and allows correlation with spatial features of the tumour ...

Please provide your email address to receive an email when new articles are posted on . Multiple CAR T-cell therapy strategies have exhibited clinical activity in recurrent glioblastoma. Early data ...

Background: Breast cancer is the most common malignancy among women globally. Organoid technology has emerged as a pivotal tool in breast cancer research due to its advantages in modeling tumor ...

Lactic acid (LA) has transitioned from being perceived as a mere glycolytic waste product to a pivotal regulator of tumor-immune crosstalk. Historical milestones—from Scheele's 1780 isolation from ...

Valarie Traynham shares what survivorship means to her, and how the definition has evolved after her diagnosis, during National Cancer Survivors Month. Survivorship can mean something different to ...

A new AI tool, AAnet, has discovered five distinct cell types within tumors, offering a deeper look into cancer's inner diversity. This insight could transform how we treat cancer, enabling more ...