A study in China found that feeding mice a high-fat diet combined with fructose syrup induces neuroinflammation and ...

The DBA/2 mouse model is an inbred mouse strain in which young DBA/2 mice are susceptible to audiogenic seizures, making them a model for epilepsy studies.

A newly identified mutation helps super-sleepers get by on just four to six hours of shut-eye per night, while the rest of us need around eight hours. Researchers described the SIK3-N783Y mutation ...

Hierarchy provides a survival advantage to social animals in challenging circumstances. In mice, social dominance is associated with trait anxiety which is regulated by adult hippocampal neurogenesis.

This period saw elevated levels of inbreeding, with approximately 61% of the sample where there was enough genomic data to analyse showing signs of inbreeding (14 out of 23).

But clinicians seeking to translate findings obtained in mice to human patients might be hampered by this very same feature—humans are, after all, a genetically diverse bunch, and this genetic ...

Inbred mice are ideal research subjects for many scientific disciplines because they are essentially genetically identical, which enables better stability and reproducibility in results ...

The most commonly used inbred strain of mice — C57BL/6J — inspired this study. After observing that C57 lab mice acted in a much more docile manner than their wild-derived counterparts, Caleb ...

Of the standard inbred mouse lines, NOD/Ltj mice were expressing the most and 129S1/Sv the least initial magazine checking (Figure 2 A, indicated with arrows), which is in accordance with previous ...

The oldest inbred BXD lines were maintained in captivity for nearly 50 years. Although each line's genome remained relatively stable, all acquired mutations and some lines acquired mutations ...