The analysis of these repeat elements revealed tissue-specific signatures of non-allelic homologous recombination, particularly in regions of chromosomes that latch on to mitotic spindles during ...

Olmos D, Lorente D, Alameda D, et al. Presence of somatic/germline homologous recombination repair (HRR) mutations and outcomes in metastatic castration-resistant prostate cancer (mCRPC) patients ...

Pathologic complete response (pCR) rates of patients with triple-negative breast cancer who were administered docetaxel plus carboplatin were significantly higher than those of patients administered ...

Homologous recombination DNA repair deficiency (HRD) is a therapeutic biomarker for sensitivity to platinum and poly (ADP-ribose) polymerase inhibitor therapies in breast and ovarian cancers. Several ...

New York – May 18, 2009: A new study published online in Nature Immunology ahead of the June 2009 print issue has found that homologous immunoglobulin (lg) alleles pair up in the nucleus at ...