Discover how lymphoid structures and germinal centers provide powerful prognostic insights into colorectal cancer.

T cell senescence occurs in the TME, affecting cancer prognosis and immunotherapy efficacy. The TME induces T cell senescence ...

Inflammation from viral infections promotes cancer metastasis, offering answers to why some cancers reawaken in humans.

Mice with a handful of cancerous cells in their lungs experienced a 100-fold increase to this number after being infected ...

New designer proteins created using an AI tool can selectively target peptide segments that bind to markers on diseased ...

David Baker’s Nobel Prize-winning lab has generated AI-designed proteins to enhance the immune system's ability to detect and ...

Current approaches in bioengineering are synthesized and methods for their implementation are suggested for the induction and modulation of trained immunity in the treatment of human diseases.

AON community oncology practices across the nation offering groundbreaking immunotherapy to expand treatment options for hard ...

Transfer of peptide-MHC complexes redirected the cytotoxicity of vaccine-primed T cells towards tumor cells irrespective of the neoantigen expression profiles.

In this valuable study, the authors provide a simple yet elegant approach to identifying therapeutic targets that synergize to prevent therapeutic resistance in ovarian cancer using cell lines, ...

Tumor-restricted activation of Vγ9Vδ2 T cells via bispecific Evobodies: a novel strategy for safe and potent immunotherapy in ovarian cancer ...

Some of the CD4+ T cell secreted proteins also correlated with their corresponding serum or plasma levels in vivo.Overall, these findings indicate that T cells in MG exhibit a skewed inflammatory ...