Wiles ran Trump’s 2016 and 2020 campaigns in Florida, helping to put the Sunshine State in his victory column both times. She also helped to score improbable statewide victories for two other Florida Republicans — U.S. Sen. Rick Scott and Gov. Ron DeSantis, though her relationship with DeSantis eventually soured.

Ms. Wiles, a principal architect of Donald J. Trump’s 2024 presidential campaign, will become the first woman to hold the job.

Wiles is well-known for her part in several Trump election campaigns, including serving as one of his two campaign managers for the 2024 ‘Make America Great Again’ campaign and the former president’s state campaign in 2016 and 2020, according to the ...