There’s rosemary, that’s for remembrance,” says Ophelia in Shakespeare’s Hamlet. So it is fitting that researchers would ...

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Department of Nuclear Medicine & PET Center & National Center for Neurological Disorders & National Clinical Research Center for Aging and Medicine, Huashan Hospital of Fudan University, Shanghai ...

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These STAs correlate with tangles in brain and with cognitive decline (Feb 2025 news). Plaque Growth. In 5xFAD mouse cortex, Aβ40 (aqua, top) deposits in more around the cores of plaque, while Aβ42 ...

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In conclusion, we created an early-stage spatiotemporal map of axonopathy in 5xFAD/Thy1-GFP-M mice and identified specific neural circuits which are vulnerable to axon lesions in an AD mouse model.

In this study, we investigated the therapeutic effects of cx-DHED and the underlying mechanism in 5xFAD mice, transgenic (Tg) mouse model of AD model mice. In several behavioral tests, such as Y-maze, ...