Learn more about the research of Mayo Clinic's Gene Editing and Cellular Engineering Laboratory led by David (Chun-Wei) D.

Leaders of the gene-editing field join forces to develop and administer the first on-demand CRISPR therapy for an infant with a rare metabolic disease. BERKELEY, Calif.-- (BUSINESS WIRE)-- #CRISPR ...

Researchers at Novartis BioMedical Research in the US and Switzerland have identified a molecular target that may provide a new therapeutic pathway for cancers driven by NRAS mutations. Findings ...

Genome-wide CRISPR/Cas9 screening identifies key profibrotic regulators of TGF-β1-induced epithelial-mesenchymal transformation and pulmonary fibrosis ...

Complementary CRISPR screen highlights the contrasting role of membrane-bound and soluble ICAM-1 in regulating antigen-specific tumor cell killing by cytotoxic T cells eLife 12:e84314.

The score plot in principal component analysis (PCA) for WT and eight transgenic yellow pea flours (TGP-2 to -9) presented in Figure 5 clearly shows the ability of this device to distinguish between ...

Researchers from Osaka University developed an in vivo CRISPR screen to analyze factors affecting Toxoplasma gondii fitness in healthy and immunodeficient mice. Mice were infected with Toxoplasma ...

Applying a CRISPR knockout screen in polarized intestinal epithelial cells and subsequent phenotypic analyses identified various genes, of which several were previously not associated with epithelial ...

When Larson and colleagues applied the screen in multiple glioblastoma cell lines, including several cell lines derived from patients, they unexpectedly found that loss of genes in the interferon ...

CRISPR screen analysis from fastq to robust statistics in Linux or Microsoft Windows. With my scripts you can analyze your own CRISPR screen completely and in a robust way with little knowledge of R, ...

The new CRISPR system could help identify targets for designing next-generation cell therapies to treat various immune disorders including autoimmune diseases and cancer, they said.