Now, Johns Hopkins Medicine scientists say they have shed new light on how bacteria protect themselves from certain phage ...

Learn about our Editorial Policies. We can target harmful bacteria. We can engineer beneficial bacteria. We can use CRISPR to study microbial interactions. We can use CRISPR to remove antibiotic ...

says Modell. The Johns Hopkins investigators say bacteria have long been known to use CRISPR-Cas systems to chop up phage DNA, break it down and get rid of it. Crucially, CRISPR systems can only ...

of invading genetic parasites like bacteriophages (phages); viruses that infect—and eventually kill—bacterial cells. They consist of two main components; the CRISPR array, which stores immune ...

Bioengineering professor and The Grainger College of Engineering's Dean, Rashid Bashir, led a team of researchers in a project that's resulted in new technology that offers rapid, highly sensitive ...

Scientists use CRISPR systems to genetically manipulate specific bacterial species, for instance those found in the mouse gut microbiome, to find new ways to promote health and treat disease. (1) ...

So why do we call it CRISPR? Cas proteins are used by bacteria to destroy viral DNA. They add bits of viral DNA to their own genome to guide the Cas proteins, and the odd patterns of these bits of ...

Of the new recruits, one system from bacteria commonly found in dairy cows shows particular promise for human health. Its efficiency is on par with the original and most widely used CRISPR-Cas ...

Crucially, CRISPR systems can only destroy DNA that matches a "memory" captured from a prior infection and stored within the bacteria's own genome, say the researchers. In this way, the CRISPR ...

Bacteria get invaded by viruses called phages. Scientists are studying how bacteria use CRISPR to defend themselves from phages, which will inform new phage-based treatments for bacterial ...