Researchers have uncovered the 3D structure of RBP3, a key protein in vision, revealing how it transports retinoids and fatty ...

In contrast, physiological cell shedding allows the renewal of the epithelial monolayer without compromising the barrier function. Here, we investigated the role of live cell extrusion in epithelial ...

Major Finding: A cancer-associated fibroblast (CAF)–epithelial cell niche shields squamous cell carcinomas (SCC) from antitumor immune responses. Concept: Epithelial JAG1–NOTCH1 signaling promotes the ...

Encelto is small, semi-permeable capsule implanted in the eye that contains allogeneic retinal pigment epithelium cells genetically engineered to produce specific therapeutic proteins. It will be ...

This cover highlights the article PLK1 inhibition delays mitotic entry revealing changes to the phosphoproteome of mammalian cells early in division by M. Gobran, P. Lenart and colleagues. HeLa Kyoto ...

Background: Although a plethora of studies have employed multiple gallbladder cancer (GBC) cell lines, it is surprisingly noted that there is still lack of a normal gallbladder epithelial cell line as ...

Few in vitro models are used to study mammary epithelial cells (MECs), and most of these do not express the estrogen receptor α (ERα). Primary MECs can be used to overcome this issue, but methods to ...