Forensic science has always relied heavily on the power of DNA to solve crimes, establish identities, and uncover hidden ...

Epigenetic reprogramming holds promise for reversing aging, addressing cellular aging mechanisms and paving the way for innovative therapeutic strategies.

meCUT&RUN detects >10-fold more DNA methylation at enhancers, gene bodies, transcription start sites, and repetitive elements, highlighting its potential for innovative studies of 5-methylcytosine in ...

PacBio was the first to detect native epigenetic modifications alongside accurate DNA sequencing. With the integration of the CUHK deep learning models, our technology will be able to detect many ...

An organism has multiple, cell type-specific, epigenomes comprising epigenetic marks such as DNA methylation ... suggesting chromatin compartments but absent topological domains (TADs) or loops.

(2023) Single-cell multi-omics reveals dynamics of purifying selection of pathogenic mitochondrial DNA across human immune cells ... multi-omic detection of mitochondrial genotypes and chromatin ...

Longitudinally measuring and forecasting changes in DNA methylation can reveal patterns of ageing ... regression using both AA computed from observed and predicted methylation values to access the ...

Certain DNA sequences can form structures other than the canonical double helix. These alternative DNA conformations—referred ...

Recent findings link DNA methylation entropy to chronological age, offering insights into epigenetic changes that could ...

We talk to Xinyue Chen about her project look at the role of methylation in memory consolidation during sleep.