Forensic science has always relied heavily on the power of DNA to solve crimes, establish identities, and uncover hidden ...

Epigenetic reprogramming holds promise for reversing aging, addressing cellular aging mechanisms and paving the way for innovative therapeutic strategies.

meCUT&RUN detects >10-fold more DNA methylation at enhancers, gene bodies, transcription start sites, and repetitive elements, highlighting its potential for innovative studies of 5-methylcytosine in ...

PacBio was the first to detect native epigenetic modifications alongside accurate DNA sequencing. With the integration of the CUHK deep learning models, our technology will be able to detect many ...

(2023) Single-cell multi-omics reveals dynamics of purifying selection of pathogenic mitochondrial DNA across human immune cells ... multi-omic detection of mitochondrial genotypes and chromatin ...

DNA demethylation of cytosines within CpG dinucleotides ... Tet1/3 thus act as determinants of CD8 T cell fates by promoting chromatin accessibility at TCR-responsive genes during T cell development.

and to chromatin compaction. In the last years the advent of more and more sensitive technologies has allowed us to greatly expand our knowledge on DNA methylation dynamics, alteration in embryos and ...