Life's instructions are written in DNA, but it is the enzyme RNA polymerase II (Pol II) that reads the script, transcribing ...
Life's instructions are written in DNA, but it is the enzyme RNA polymerase II (Pol II) that reads the script, transcribing ...
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Sequences that form DNA secondary structures, ...
Eukaryotic Polα-primase contains DNA polymerase (Pol1) and RNA primase subunits that together synthesize a >20-nucleotide hybrid RNA–DNA primer. Bacteria and archaea only require a dozen or less RNA ...
A common mechanism for recruiting the Rrm3 and RTEL1 accessory helicases to the eukaryotic replisome
The eukaryotic replisome is assembled around the CMG (CDC45-MCM-GINS) replicative helicase, which encircles the leading-strand DNA template at replication forks. When CMG stalls during DNA replication ...
Abstract: Origins of replication sites (ORIs) are crucial genomic regions where DNA replication initiation takes place, playing pivotal roles in fundamental biological processes like cell division, ...
Two proteins form a stable complex to establish physical barriers that hinder the copy of certain regions of DNA in the cells of fruit fly larvae. Open annotations (there are currently 0 annotations ...
Type II topoisomerases modulate chromosome supercoiling, condensation, and catenation by moving one double-stranded DNA segment through a transient break in a second duplex. How DNA strands are chosen ...
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