Homologous recombination is associated with Holliday junctions that aid in the pairing of DNA helices. Different pathways can produce crossover and non-crossover products, and this is vital for ...

View of an intermediate from the homologous recombination reaction. This intermediate shows a mini filament, with its nine RecA proteins in gold and its single-stranded DNA in brown, after a ...

Pathologic complete response (pCR) rates of patients with triple-negative breast cancer who were administered docetaxel plus carboplatin were significantly higher than those of patients administered ...

Homologous recombination DNA repair deficiency (HRD) is a therapeutic biomarker for sensitivity to platinum and poly (ADP-ribose) polymerase inhibitor therapies in breast and ovarian cancers. Several ...

Frank Hartung, Stefanie Suer, Holger Puchta, Two Closely Related RecQ Helicases Have Antagonistic Roles in Homologous Recombination and DNA Repair in Arabidopsis Thaliana, Proceedings of the National ...