A protein that stops cells from dividing in response to damage or stress could be a new biomarker or therapeutic target for ...

Lipid metabolism has emerged as a central player in the progression and therapy resistance of breast cancer, particularly the aggressive subtype known as triple-negative breast cancer (TNBC).

Our immune systems weaken as we get older, making fewer cells that fight infection and help us recover from illness and ...

New research has uncovered a surprising culprit underlying cardiovascular diseases in obesity and diabetes -- not the presence of certain fats, but their suppression. The study challenges the ...

Traumatic brain injuries, often resulting from falls or traffic accidents, lead to significant death and disability each year ...

At least four other companies are also testing innovative drugs that block the body’s production of Lp(a), a mix of lipids and a protein. Dr. David Maron, a preventive cardiologist at Stanford ...

Elevated lipoprotein(a) concentrations are associated with atherosclerotic cardiovascular disease. The safety and efficacy of lepodisiran, an extended-duration, small interfering RNA targeting ...

Weiner, Ph.D., have described a next-generation vaccination technology that combines plasmid DNA with a lipid nanoparticle (LNP) delivery system. The research was conducted in collaboration with ...

However, in the presence of calcium, this pattern reverses—calcium slows down the polymerization of pure TA while enabling mixed solutions to polymerize. "This suggests that calcium availability ...

Also, the role of lipid‐lowering therapy in the association is unclear. The study aimed to examine the longitudinal associations of RC with cognitive decline by lipid‐lowering drug use during ...

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At the same time, UVC promotes cytochrome c-catalyzed cardiolipin peroxidation, which increases lipid ROS, and PARylated GSDME senses these oxidative stresses, leading to oxidative polymerization and ...