In contrast, physiological cell shedding allows the renewal of the epithelial monolayer without compromising the barrier function. Here, we investigated the role of live cell extrusion in epithelial ...

Tubular epithelial cells (TECs ... using a fluorescence microscope (Leica, Thunder Imager). Kidney specimens were preserved in 4% paraformaldehyde, encased in paraffin, and subsequently cut into ...

Get Instant Summarized Text (Gist) A new method for growing iPS cell-derived kidney progenitor cells has been developed, potentially advancing renal regenerative therapies. In mouse models of ...

Nevertheless, such observations are complex─they require delicate samples kept in the liquid phase, low electron dose, and proper cell viability verification methods. Despite being highly demanding, ...

Epithelial-to-mesenchymal transition in tRCC is accompanied by enrichment in myofibroblastic cancer-associated-fibroblasts and poor patient outcome. Translocation renal cell carcinoma (tRCC) is a rare ...

Polymer Science, Zernike Institute for Advanced Materials (ZIAM), University of Groningen, Groningen 9747AG, The Netherlands Department of Pathology and Medical Biology, University of Groningen, ...

The European Association of Urology (EAU) renal cell carcinoma (RCC) guideline panel has updated their evidence-based guidelines and recommendations for the management of RCC. Here we present a ...

After sufficient staining, the slides ... epithelial cells; Black arrow: necrotic cells. Scale bars, 200 µm. UUTD refers to abnormal urodynamics of the upper urinary tract that interferes with its ...

remodeling from a ring-like anastomosis under the nascent renal pelvis; a site of VEGF-C expression, to form a patent vascular plexus. We identified a heterogenous population of lymphatic endothelial ...

Here, we investigate how the actomyosin scaffold protein anillin contributes to epithelial mechanics in Xenopus laevis embryos. Increased mechanosensitive recruitment of vinculin to cell–cell ...