Inflammation from viral infections promotes cancer metastasis, offering answers to why some cancers reawaken in humans.

New designer proteins created using an AI tool can selectively target peptide segments that bind to markers on diseased ...

David Baker’s Nobel Prize-winning lab has generated AI-designed proteins to enhance the immune system's ability to detect and ...

Current approaches in bioengineering are synthesized and methods for their implementation are suggested for the induction and modulation of trained immunity in the treatment of human diseases.

AON community oncology practices across the nation offering groundbreaking immunotherapy to expand treatment options for hard ...

Transfer of peptide-MHC complexes redirected the cytotoxicity of vaccine-primed T cells towards tumor cells irrespective of the neoantigen expression profiles.

In this valuable study, the authors provide a simple yet elegant approach to identifying therapeutic targets that synergize to prevent therapeutic resistance in ovarian cancer using cell lines, ...

In a paper published in Science Bulletin, the research team led by Professor Wen Zhang from the Department of Rheumatology and Immunology at Peking Union Medical College Hospital (PUMCH) has made ...

Some of the CD4+ T cell secreted proteins also correlated with their corresponding serum or plasma levels in vivo.Overall, these findings indicate that T cells in MG exhibit a skewed inflammatory ...

Antigen-presenting cells continue to stimulate activation and proliferation of T cells and form a vicious cycle of lymphohistiocytic proliferation and hypercytokinemia, ultimately leading to ...

Therapeutic activation of the stimulator of interferon genes (STING) innate immune pathway shows promise for cancer immunotherapy; however, frequent loss of STING expression in cancer cells renders ...