Novel Drug Safe, Effective for Acute Schizophrenia - Medscape
May 23, 2025 · The novel PDE10A inhibitor CPL'36 offers a new mechanism of action and is both safe and effective for acute exacerbations of schizophrenia, new research suggests.
Forget the Tremor: These Symptoms Come First in Parkinson’s
Jun 10, 2025 · It often appears alongside other signs like a softer, monotone voice or reduced arm swing while walking — both early signs of extrapyramidal dysfunction.
'Impressive' New Data on Novel Schizophrenia Hopeful KarXT
May 8, 2024 · The novel investigational antipsychotic KarXT was effective and well tolerated in adults with schizophrenia experiencing acute psychosis in a second phase 3 trial.
Treatment Considerations for Psychiatric Syndromes Associated …
Another important consideration is HIV-infected patients' increased sensitivity to antipsychotic-induced extrapyramidal symptoms, thought to be related to the damage to basal ganglia …
Definition of Drug-Induced Cognitive Impairment in the Elderly
Jun 14, 2000 · Neuroleptic malignant syndrome is characterized by delirium, fever, autonomic dysfunction, extrapyramidal syndrome, and recent history of antipsychotic use. [9, 18] One …
Man With Exploding Head Syndrome Responds to Ketamine
2 days ago · A man with long-standing exploding head syndrome and sleep paralysis reports fewer and less intense episodes after low-dose ketamine following multiple unsuccessful …
Delayed Sleep-Wake Phase Disorder in Teens Often Missed
2 days ago · The delayed sleep-wake phase in adolescents often overlaps with ADHD and restless legs syndrome, worsening insomnia and academic performance and calling for early …
Positive Phase 3 Results for Antipsychotic in Schizophrenia
Jan 12, 2024 · The investigational antipsychotic KarXT is effective in reducing positive and negative symptoms of schizophrenia, with a favorable side-effect profile in the pivotal …
Dermatologic Emergencies Clinicians Must Not Miss - Medscape
A true dermatologic emergency is a skin disorder that threatens life or functional outcomes and requires immediate treatment. These emergencies include allergic reactions and severe skin ...
LAIs Tied to Lower Relapse, Mortality Risk in Schizophrenia
Oct 16, 2025 · Long-acting injectable antipsychotics are linked to a lower risk for disease relapse and mortality than oral antipsychotics in adults with schizophrenia, a new study shows.