Factor IX (EC 3.4.21.22), also known as Christmas factor, is one of the serine proteases involved in coagulation; it belongs to peptidase family S1. Deficiency of this protein causes haemophilia B.

This wealth of knowledge has revealed how the factor IX gene and protein evolved, how factor IX is regulated, how it functions within the coagulation cascade, and how structural changes …

Hemophilia B, also called factor IX (FIX) deficiency or Christmas disease, is a genetic disorder caused by missing or defective factor IX, a clotting protein. Although it is passed down from …

May 1, 2025 · Factor IX is a protein produced naturally in the body. It helps the blood form clots to stop bleeding. Injections of factor IX are used to treat hemophilia B, which is sometimes called …

Nov 21, 2024 · Coagulation factor IX plays a central role in hemostasis through interaction with factor VIIIa to form a factor X–activating complex at the site of injury. The absence of factor IX …

Jan 6, 2026 · Factor IX is a protein that circulates in the blood, playing a role in the body’s ability to stop bleeding. Also known as Coagulation Factor IX, it is synthesized in the liver and …

Factor IX is a vitamin K-dependent zymogen that, when absent or deficient, results in a bleeding disorder called hemophilia B. It is activated by either factor XIa/Ca++ or factor VIIa/tissue …

Jun 24, 2025 · Factor IX, also known as Christmas factor, is a vitamin K-dependent clotting factor that plays a crucial role in the coagulation cascade. It is a serine protease enzyme that is …

The F9 gene provides instructions for making a protein called coagulation factor IX. Coagulation factors are a group of related proteins that are essential for the formation of blood clots. After …

Factor IX injection helps control bleeding in people with hemophilia B, a bleeding disorder that prevents your blood from clotting. The injection helps your blood clot.