Intracerebroventricular injection (often abbreviated as ICV injection) is a route of administration for drugs via injection into the cerebral ventricles so that it reaches the cerebrospinal fluid (CSF).

Jul 1, 2018 · ICV drug delivery is an established route of drug administration into the CNS and can be performed safely when stringent measures are taken to minimize complications.

Here, we present an optimized ICV injection of T cells with improved injection efficiency at pathological sites within the brain parenchyma. We describe details of the surgical procedure …

Apr 22, 2025 · Intracerebroventricular (ICV) injection is a valuable, albeit technically demanding, route for delivering therapeutics directly to the CNS in preclinical research and specific clinical …

Apr 22, 2023 · Abstract Intracerebroventricular (ICV) administration is increasingly being explored as a means for delivering antiseizure and antiepileptic therapies to epileptic brain tissue.

Intracerebroventricular injection is a method used in neuroscience to inject substances into the brain ventricles. This technique allows for the direct delivery of drugs or other substances to …

May 10, 2021 · Animals were treated by either direct intracerebroventricular (ICV) injection, by intrathecal (IT) infusion into the cerebrospinal fluid, or by intranasal (IN) instillation of AAV9 …

Apr 29, 2025 · Intracerebroventricular (ICV) injection is a widely used technique in neuroscience research, allowing direct delivery of substances into the cerebrospinal fluid. This method …

Feb 1, 2017 · As an intrathecal delivery method, the intracerebroventricular (ICV) route of administration instills therapy into the cerebral ventricles via an ICV port implanted under the …

Nov 14, 2025 · Intracerebroventricular (ICV) injection is a specialized technique used extensively in preclinical research. This method involves the precise delivery of substances, such as …